Essential Bioinformatics for Global LeadersⅠ 2017年10月4日開講 

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10月4日より、Essential Bioinformatics for Global LeadersⅠを開講いたします。この科目はグローバル理工学副専攻の履修科目になっていますが、博士前期・後期課程に所属し、関心のある学生であれば、どなたでも履修することができます。なお、講義は英語で行われます。

本講座の趣旨

Prof. GouraudBioinformatics is an interdisciplinary research area at the interface between biological science and computational science, the ultimate goal of which is to better understand living cells and their functioning at the molecular level. It involves the technologies that use computers for the storage, retrieval, manipulation, understanding and distribution of information related to biological macromolecules such as DNA, RNA, protein, and even more.
The “Essential Bioinformatics for Global Leaders I” classes has been conceived for non-biologist as well as biologist students wishing to acquire global leader skills and enrich their scientific English. This first series of interactive classes, given in friendly English, will provide the students with the fundamental cellular and molecular biology knowledge needed to understand bioinformatics. Important notions of bioinformatics, its logical background and its cutting-edge applications in basic biology research, biotechnology and biomedical sciences will also be introduced. The classes include lectures, discussion and practices [wet lab (basic molecular biology experiments) and dry lab (databases exploration, data analysis using software)]. The students do not need to understand the mathematical details in the field.

学生へのメッセージ

These interactive classes are open to everyone, from biological background or not. They will provide you with the basis for a general understanding of cell and molecular biology. If you are new to Biological Sciences, you will have a chance to do your first biological experiments. If you already know about the field, it will be a great opportunity for you to improve your skills, widen your knowledge and in any cases listen and practice your English! Do not hesitate to join that fun experience!

講義概要

科目名
Essential Bioinformatics for Global LeadersⅠ [17S1003
単位数
2.0単位
担当教員
Gouraud, Sabine (お茶の水女子大学プロジェクト教育研究院特任准教授)
対象
博士前期・後期課程
日時・場所
10/04 5~6限(13:20-14:50)人間文化研究科棟408室
10/11 5~6限(13:20-14:50)人間文化研究科棟408室
10/18 5~6限(13:20-14:50)人間文化研究科棟408室
10/25 5~6限(13:20-14:50)人間文化研究科棟408室
11/01 5~6限(13:20-14:50)人間文化研究科棟408室
11/08 5~6限(13:20-14:50)人間文化研究科棟408室
11/15 5~8限(13:20-16:30)理学部1号館521室
11/22 5~6限(13:20-14:50)理学部2号館202室
11/29 5~6限(13:20-14:50)理学部2号館202室
12/06 5~8限(13:20-16:30)理学部1号館521室
12/13 5~8限(13:20-16:30)理学部1号館521室
12/20 5~6限(13:20-14:50)人間文化研究科棟408室
授業計画

1) Oct 4th, 2017: 90 min, Graduate School of Humanities room 408
Introduction to the “Essential Bioinformatics for Global Leader I” classes and general bioinformatics concept [style: lecture, discussion]
-Program of the classes, expectation of students
-History, general definition/overview of bioinformatics and its applications in different fields of science.

2) Oct 11th, 2017: 90 min, Graduate School of Humanities room 408
Basics of molecular biology I [style: lecture, discussion]
Introduction to the cell, organization and composition, cells in their context (models of cells, cancer, infection, development, tissue renewal…)

3) Oct 18th, 2017: 90 min, Graduate School of Humanities room 408
Basics of molecular biology II [style: lecture, discussion, computer practice]
PROTEIN, structure/function, analytical techniques and tools, proteomics databases exploration

4) Oct 25th, 2017: 90 min, Graduate School of Humanities room 408
Basics of molecular biology III [style: lecture, discussion, computer practice]
DNA, structure, basic genetic mechanisms (RNA, mutation, SNP, gene repair, replication, protein translation, evolution…..), analytical techniques and tools, genomics databases exploration.

5) Nov 1st, 2017: 90 min, Graduate School of Humanities room 408
Basics of molecular biology IV [style: lecture, discussion]
Omics and Bioinformatics; new molecular techniques, application and social implication of biological investigation, discussion over scientific papers.

6) Nov 8th, 2017: 90 min, Graduate School of Humanities room 408
RT-qPCR, primer construction [style: lecture, discussion, computer practice]
NCBI sequence database, how to make primers and PCR (NCBI Database/sequence alignment)

7-8) Nov 15th, 2017: 180 min, Science building 1, Practice room 521
RNA isolation [style: wet lab]
RNA extraction from animal tissue/cells (Guanidinium thiocyanate-phenol-chloroform method), RNA quantitation assessment (Nanodrop)

9) Nov 22nd, 2017: 90 min, Science building 2 room 202
RNA quality assessment [style: wet lab]
Bioanalyzer use+ sample preparation for next experiments

10) Nov 29th, 2017: 90 min, Science building 2 room 202
Gene expression analysis [style: wet lab, computer practice, discussion]
RT-qPCR (data analysis using thermal cycler software, PCR products gel electrophoresis)

11-12) Dec 6th, 2017: 180 min, Science building 1, Practice room 521
Protein expression analysis I [style: wet lab]
Protein extraction from animal tissue/cells, protein quantitation, protein separation by acrylamide gel electrophoresis (western-blotting)

13-14) Dec 13th, 2017: 180 min, Science building 1, Practice room 521
Protein expression analysis II [style: wet lab, computer practice, discussion]
Semi-quantitative western-blotting (immunoblotting, Image J data analysis)
Conclusion/discussion

15) Dec 20th, 2017: 90 min, Graduate School of Humanities room 408
Example of small scale high-throughput transcriptomic methods (PCR array), discussion over scientific paper.

教科書・参考文献
Essential Cell Biology (Garland Science), Molecular Biology of the Cell(Garland Science), Bioinfomratics for Beginners (Academic Press) Supratim Choudhuri

履修登録

履修登録期間: 10月 2日(月)~ 10月14日(土)
上記登録期間内に登録ができなかった場合は、学生センター棟1階学務課にご相談ください。

お問合せ

お茶の水女子大学 リーディング大学院推進センター
Tel: 03-5978-5775
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