Essential Bioinformatics for Global LeadersⅠ 2015年10月7日開講

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Prof. Gouraud イノベーションを起こす人材となるための要件は、専門分野において学位を授与されるレベルの深い専門性をもち、物理・数学・情報の異なる専門分野にまたがる新たな課題を見出し解決していくだけの基盤力を有することです。グローバル理工学副専攻では、基盤力強化のためのコースワーク(イノベーション創成基盤科目)を設置しています。
 この度、このコースワークから、Essential Bioinformatics for Global LeadersⅠを開講することになりました。講師は、お茶の水女子大学プロジェクト教育研究院のGouraud特任准教授が担当します。
 この科目は、グローバル理工学副専攻の履修科目になっていますが、博士前期・後期課程に所属する学生で関心のある方は、どなたでも履修することができます。なお、講義は英語で行われます。

本講座の趣旨

Bioinformatics is an interdisciplinary research area at the interface between biological science and computational science, the ultimate goal of which is to better understand living cells and their functioning at the molecular level. It involves the technologies that use computers for the storage, retrieval, manipulation, understanding and distribution of information related to biological macromolecules such as DNA, RNA, protein, and even more.
The “Essential Bioinformatics for Global Leaders I” classes has been conceived for non-biologist as well as biologist students wishing to acquire global leader skills and enrich their scientific English. This first series of interactive classes, given in friendly English, will provide the students with the fundamental cellular and molecular biology knowledge needed to understand bioinformatics. Important notions of bioinformatics, its logical background and its cutting-edge applications in basic biology research, biotechnology and biomedical sciences will also be introduced. The classes include lectures, discussion and practices [wet lab (basic molecular biology experiments) and dry lab (databases exploration, data analysis using software)]. The students do not need to understand the mathematical details in the field.

講義概要

科目名 Essential Bioinformatics for Global LeadersⅠ [15S1003]
講師 Sabine Gouraud (お茶の水女子大学プロジェクト教育研究院特任准教授)
対象 博士前期・後期課程
内容 日時 場所 講義テーマ
10月7日(水)
13:20~14:50
人間文化研究科棟408室 1) Oct 7th, 2015: 90min, Graduate School of Humanities room 408
Introduction to the “Essential Bioinformatics for Global Leader I” classes and general bioinformatics concept [style: lecture, discussion]
-Program of the classes, expectation of students
-History, general definition/overview of bioinformatics and its applications in different fields of science.

2) Oct 14th, 2015: 90 min, Graduate School of Humanities room 408
Basics of molecular biology I [style: lecture, discussion]
Introduction to the cell, organization and composition, cells in their context (models of cells, cancer, infection, development, tissue renewal…)

3) Oct 21st, 2015: 90 min, Graduate School of Humanities room 408
Basics of molecular biology II [style: lecture, discussion, computer practice]
PROTEIN, structure/function, analytical techniques and tools, proteomics databases exploration

4) Oct 28st, 2015: 90 min, Graduate School of Humanities room 408
Basics of molecular biology III [style: lecture, discussion, computer practice]
DNA, structure, basic genetic mechanisms (RNA, mutation, SNP, gene repair, replication, protein translation, evolution…..), analytical techniques and tools, genomics databases exploration.

5) Nov 4th, 2015: 90 min, Graduate School of Humanities room 408
Basics of molecular biology IV [style: lecture, discussion]
Omics and Bioinformatics; new molecular techniques, application and social implication of biological investigation, discussion over scientific papers.

6-7) Nov 11th, 2015: 180 min, Science building 1, Practice Room 521
RNA isolation [style: wet lab]
RNA extraction from animal tissue/cells (Guanidinium thiocyanate-phenol-chloroform method), RNA quantitation & quality assessment (Nanodrop & Bioanalyzer)

8-9) Nov 18th, 2015: 180 min, Science building 2, Practice room 405
Gene expression analysis I [style: computer practice, discussion, wet lab]
How to make primers (NCBI Database/sequence alignment), RT-qPCR preparation

10) Nov 25th, 2015: 90 min, Science building 2, Practice Room 405
Gene expression analysis II [style: wet lab, computer practice, discussion]
RT-qPCR (data analysis using thermal cycler software, PCR products gel electrophoresis)
Example of small scale high-throughput transcriptomic methods (PCR array)

11-12) Dec 2nd, 2015: 180 min, Science building 1, Practice Room 521
Protein expression analysis I [style: wet lab]
Protein extraction from animal tissue/cells, protein quantitation, protein separation by acrylamide gel electrophoresis (western-blotting)

13) Dec 9th, 2015: 90 min, Science building 1, Practice room 521
Protein expression analysis II [style: wet lab, computer practice, discussion]
Semi-quantitative western-blotting (immunoblotting, Image J data analysis)
Example of small scale high-throughput proteomic methods (antibody array, DNA/protein interaction)

14) Dec 16th, 2015: 90 min, Science building 1, Practice room 521
Immunohistochemistry I [style: wet lab]
Rat brain slicing, immunofluorescence (staining of free floating brain sections with specific antibodies and their fluorescent dyes to specifically localize a protein into cells/tissues).

15) Jan 6th, 2016: 90 min, Science building 2 room 404
Immunohistochemistry II [style: wet lab, discussion]
Confocal microscopy, immunofluorescence data analysis.
Notion of Neuroinformatics.

10月14日(水)
13:20~14:50
人間文化研究科棟408室
10月21日(水)
13:20~14:50
人間文化研究科棟408室
10月28日(水)
13:20~14:50
人間文化研究科棟408室
11月4日(水)
13:20~14:50
人間文化研究科棟408室
11月11日(水)
13:20~16:30
理学部1号館521室
11月18日(水)
13:20~16:30
理学部2号館405室
人間文化研究科棟408室
11月25日(水)
13:20~14:50
理学部2号館405室
12月2日(水)
13:20~16:30
理学部1号館521室
12月9日(水)
13:20~14:50
理学部1号館521室
12月16日(水)
13:20~14:50
理学部1号館521室
1月6日(水)
13:20~14:50
理学部2号館404室

講義のチラシはこちらからご覧になれます。

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