Class List of Fall Semester 2018
“Essential Bioinformatics for Global LeadersⅠ” will begin on October 3. This is a class for students in “Minor Course of Science and Technology for Global Leaders”. But all master’s & doctoral students can take it if you have interest. The class will be conducted in English.
Theme & Objective
Bioinformatics is an interdisciplinary research area at the interface between biological science and computational science, the ultimate goal of which is to better understand living cells and their functioning at the molecular level. It involves the technologies that use computers for the storage, retrieval, manipulation, understanding and distribution of information related to biological macromolecules such as DNA, RNA, protein, and even more. The “Essential Bioinformatics for Global Leaders I” classes has been conceived for non-biologist as well as biologist students wishing to acquire global leader skills and enrich their scientific English. This first series of interactive classes, given in friendly English, will provide the students with the fundamental cellular and molecular biology knowledge needed to understand bioinformatics. Important notions of bioinformatics, its logical background and its cutting-edge applications in basic biology research, biotechnology and biomedical sciences will also be introduced. The classes include lectures, discussion and practices [wet lab (basic molecular biology experiments) and dry lab (databases exploration, data analysis using software)]. The students do not need to understand the mathematical details in the field.
Message to Students
These interactive classes are open to everyone, from biological background or not. They will provide you with the basis for a general understanding of cell and molecular biology. If you are new to Biological Sciences, you will have a chance to do your first biological experiments. If you already know about the field, it will be a great opportunity for you to improve your skills, widen your knowledge and in any cases listen and practice your English! Do not hesitate to join that fun experience!
Lecture Outline
| Subject |
|---|
| Essential Bioinformatics for Global LeadersⅠ [18S1003] |
| Number of Credits |
| 2.0 |
| Instructor |
| Gouraud, Sabine (Project Associate Professor of Ochanomizu University) |
| Target Audience |
| Graduate Students |
| Date, Time and Location |
|
Wednesday October 3, Period 5-6 (13:20-14:50) Graduate School of Humanities & Sciences Building R408 October 10, Period 5-6 (13:20-14:50) Graduate School of Humanities & Sciences Building R408 October 17, Period 5-6 (13:20-14:50) Graduate School of Humanities & Sciences Building R408 October 24, Period 5-6 (13:20-14:50) Graduate School of Humanities & Sciences Building R408 October 31, Period 5-6 (13:20-14:50) Graduate School of Humanities & Sciences Building R408 November 7, Period 5-6 (13:20-14:50) Graduate School of Humanities & Sciences Building R408 November 14, Period 5-8 (13:20-16:30) Science building 1 R521 November 21, Period 5-6 (13:20-14:50) Science building 2 R202 November 28, Period 5-6 (13:20-14:50) Science building 2 R202 December 5, Period 5-8 (13:20-16:30) Science building 1 R521 December 12, Period 5-8 (13:20-16:30) Science building 1 R521 December 19, Period 5-6 (13:20-14:50) Science building 2 R202 |
| Lecture Plan |
|
Class 1- Introduction to the “Essential Bioinformatics for Global Leader I” classes and general bioinformatics concept [style: lecture, discussion] History, general definition/overview of bioinformatics and its applications in different fields of science. Class 2- Basics of molecular biology I [style: lecture, discussion] Introduction to the cell, organization and composition, cells in their context (models of cells, cancer, infection, development, tissue renewal…) Class 3- Basics of molecular biology II [style: lecture, discussion, computer practice] PROTEIN, structure/function, analytical techniques and tools, proteomics databases exploration Class 4- Basics of molecular biology III [style: lecture, discussion, computer practice] DNA, structure, basic genetic mechanisms (RNA, mutation, SNP, gene repair, replication, protein translation, evolution…), analytical techniques and tools, genomics databases exploration. Class 5- Basics of molecular biology IV [style: lecture, discussion] Omics and Bioinformatics; new molecular techniques, application and social implication of biological investigation. Class 6- RT-qPCR technique and primers design [style: lecture, discussion, computer practice] NCBI Database Class 7-8- RNA isolation [style: wet lab] RNA extraction from animal tissue (Guanidinium thiocyanate-phenol-chloroform method), RNA quantitation assessment (Nanodrop) Class 9- RNA quality assessment [style: wet lab] Bioanalyzer Class 10- Gene expression analysis I [style: wet lab] RT-qPCR experiment Class 11-12- Gene expression analysis II [style: computer practice, discussion] RT-PCR data analysis-Example of small scale high throughput transcriptomics method (PCR array) Class 13-14- Protein expression analysis I [style: wet lab, computer practice, discussion] Semi-quantitative Western-Blotting experiment(gel electrophoresis, immunoblotting) Class 15- Protein expression analysis II [style: wet lab, computer practice, discussion] Semi-quantitative Western-Blotting, data analysis (Image J) |
| Out-of-class Learning |
| Students might be asked to perform simple data analysis to practice the methods seen during the class |
| Textbook/Reference |
| Essential Cell Biology (Garland Science) + Molecular Biology of the Cell (Garland Science) + NCBI databases |
Registration
Registration Period: Mon., October 1 through Sat., October 13
If you cannot register during above period, please contact Academic Affairs Office in Student Affairs Building.
Contact
Ochanomizu University Leading Graduate School Promotion Center
Tel: 03-5978-5775
E-mail:
